The unexpected traits associated with core promoter elements
نویسندگان
چکیده
منابع مشابه
The unexpected traits associated with core promoter elements.
The core promoter of eukaryotic coding and non-coding genes that are transcribed by RNA polymerase II (RNAP II) is composed of DNA elements surrounding the transcription start site. These elements serve as the docking site of the basal transcription machinery and have an important role in determining the position and directing the rate of transcription initiation. This review summarizes the cur...
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Downstream elements are a newly appreciated class of core promoter elements of RNA polymerase II-transcribed genes. The downstream core element (DCE) was discovered in the human beta-globin promoter, and its sequence composition is distinct from that of the downstream promoter element (DPE). We show here that the DCE is a bona fide core promoter element present in a large number of promoters an...
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ژورنال
عنوان ژورنال: Transcription
سال: 2011
ISSN: 2154-1264,2154-1272
DOI: 10.4161/trns.2.5.17271